I like the storyline of this show,it attract me so much

This movie was so-so. It had it's moments, but wasn't the greatest.

The movie is wonderful and true, an act of love in all its contradictions and complexity

By the time the dramatic fireworks start popping off, each one feels earned.

I had to watch this in school in 8th grade science. Overall, this movie is ok I guess. Everything that is live-action is disgusting and terrible. The animation parts are entertaining and clever. I wouldn't recommend this movie, but its not terrible. There isn't much to say about this movie other than that really.

While, this animation movie might appeal to somebody with somewhat bad taste like me. The truth is, that the film doesn't work for everybody. Don't get me wrong, there were plenty of somewhat sophistical & adult-driven clever pun-entertaining moments in the animation sequences directed by Tom Sito if you like this movie & the animation wasn't half bad, even if the very noticeable poor early CGI mixed with hand-drawn, made this film, a bit dated. It was still somewhat beautiful. However, the life-action, unfunny childish toilet humor sequences from the Farrelly brothers, kinda dumb down, the film to standstill. Because of that, I can't say, this movie is a good movie. Nevertheless, I also can't say, it's awful. It's somewhat in the middle. Still, there is plenty of flaws in the film to point out. One of the biggest complains of the movie produced by Warner Bros, is the fact that the life action scenes with Frank Detorre (Bill Murray) doesn't intermixed well, with the hand-drawn animation in his body. It's kinda jarring to see, actors reenacted short scenes on camera film footage, only to be badly edited into a film, mostly, full of animation cels. In my opinion, the whole movie should be, all animated! Yes, I know, it would be, more expensive to produce, but at least, the movie would had been, a little more, well-made. Another problem between the live action and animation parts is the pacing. While, the animation move in a pretty solid action pack pace, with white blood cell, officer Osmosis Jones (Voiced by Chris Rock) having to team up, with a cold pill, Drixenol "Drix" Koldreliff (Voiced by David Hyde Pierce), in order to stop a deadly virus, known as Thrax (Voiced by Laurence Fishburne) from killing Frank in a pretty generic buddy cop clichés storyline. I really didn't care for the repetitive gross out and pointless dialogue scenes that they gave Bill Murray to do. Honestly, without spoiling the movie, too much, there was no reason, why Frank needed to reenact with comedian, Molly Shannon's character, as she wasn't any help nor a major foe for Frank. The film would be, better off, without her. Have the film establish, that Jones accidentally causing the death of Frank's wife, by allowing a virus to escape Frank's body, instead of him, causing the vomiting at the science fair, that got Frank in trouble. At least, the movie would had more stalks, plus it would be a better backstory and reason, why the depressed Frank is letting himself go, health wise than what the film gave Murray, with Frank being annoying clueless and too unlikeable lazy at being healthy. Also, I think the movie would had made more sense, if Frank was working at a desk job at the zoo, rather than the field. Why? It's because, it just hard to believe, that Frank would be, really that unhealthy with all the manual back breaking work, he does, like shoveling and washing animals in the hot sun. A desk job works better, because of the lack of physical activity. Sadly, the movie doesn't do this, and the live action scenes really dragged. Honestly, the whole conflict with Frank, choosing a trip to Buffalo over his daughter, Shane (Elena Franklin) camping trip was also not needed. Regardless of him, going or not, Frank's health would had still decline, due to Thrax. Also, with all anthropomorphization aside, anyone who's passed a biology class knows that germs & viruses don't work even remotely like they're depicted in the film. Though they can be harmful to the host that they infest, they aren't biologically programmed to quickly kill it. They mostly reproduce by multiplying and spreading throughout its body over time, feeding on the resources. Any harmful symptoms are simply side-effects of over population and damage of cells. Regardless of the artistic license with the science. Laurence Fishburne was amazing as the villain. The things, his character does, is very haunting and his voice acting matches that. It really surprised me, that's this movie was PG, seeing, how Thrax rips, another germ apart, and cause, a saliva boat to explode in flames. I thought, it would be, at least, PG-13, due to the violence and bodily humor. It didn't help that the lyrics to the Kid Rock's song wasn't kid-friendly as well. This movie is surely, not PG! Gross humor, aside, I didn't like, how the film handle the mentally handicap, obesity, and other issues. Regardless of the botch crudely done moral message, 'Osmosis Jones' is still truly imaginative, innovative and fun with alright voice acting work, even if main star, Chris Rock was a bit annoying with all his standard, generic cockiness, yelling. Still, I felt like I need a detox, after watching this film. Like Junk Food, films like this, should make up a minimal part of your life. Not fully. For the sake of your loves ones. Just stick to healthy & smarter animation choices like 2015's 'Inside Out'. But if you want to junk out on something really childish. Then, you got this film. This autopsy of a mess.

Osmosis Jones (2001): Dir (live): Bobby Farrelly, Peter Farrelly / Dir (animated scenes): Piet Kroon, Tom Sito / Cast: Bill Murray, Molly Shannon, Chris Elliott, Elena Franklin / Voices: Chris Rock: Creative and unique animation. Bill Murray plays an out of shape father who is constantly warned by his daughter to watch his eating habits. Soon a deadly virus begins to spread throughout his body. It is up to animated blood cell Osmosis Jones and his partner Drix to destroy evil virus Thrax. Live footage is directed by Peter and Bobby Farrelly who are famous for great comedies such as Kingpin and There's Something About Mary. Animated sequences are directed by Piet Kroon and Tom Sito who are given the best part of the film. Animated characters are cool and carry the film but the live performances are flat. Bill Murray holds his own as this unhealthy eater who ends up in the down and out and must rely on Jones to triumph and recreate his health. Molly Shannon has the misfortune of having a zit explode on her face. Chris Elliott has a cardboard role of Murray's brother and co-worker. Elena Franklin is flat as Murray's daughter who cares for her father and his welfare. The voice talents fare much better with Chris Rock leading the way as the free spirited Osmosis Jones whose mission is to render Bill Murray healthy. Creative and well meaning comedy about responsible living. Score: 7 / 10

This movie includes a bit of humor that I didn't care for, and a lot of other people probably won't either, but it's definitely worth getting over for the extremely original plot and plenty of other fun aspects.This is an unusual narrative that includes both animation and live action; it's not like in "Who Framed Roger Rabbit" or (shudder) "Cool World" where the animated characters mingle with live action ones, it jumps between worlds. The animated world takes place inside Frank Detorre's (Bill Murray's) body, where white blood cells behave like police officers and viruses behave like criminals, living in Frank's body as if it were a city. The City of Frank is run by an irresponsible mayor who has lead to a huge decline in the slovenly Frank's health. Frank ingests an extremely lethal virus named Thrax, and it's up to blacklisted cop Osmosis Jones and cold pill Drixenol to stop him before it's too late. Even in animated form, some of the humor is a little hard to stomach (no pun intended), though not as much as the live action parts. It's interesting that other movies that take place inside the human body like "Fantastic Voyage" or "Innerspace" are actually live action in their entirety, but are definitely less grotesque. The animation is done well, it's energetic and visually appealing. It's fun to see how exactly different sections of the body translate into the concept of it being a city, the zit, the nose, and the brain being the most imaginative areas.Thrax is a cool villain, and he actually kills quite a few characters in various gruesome and brutal ways on screen, which isn't something you'll usually see in a film primarily targeted at younger viewers. Osmosis Jones and Drix make for good protagonists, each having their own troubles they come to terms with. Their relationship is a bit stereotypical buddy cop movie style at times, but there's definitely some good stuff regarding Ozzie's past mistakes and Drix's fears of being ultimately useless.The live action side of things isn't as good as the animation, but it still has its moments. I'm a big fan of Bill Murray, and though he's still funny at times in this, it's definitely not his best work. The live action gross out humor is never outright disgusting, but things like the throbbing zit popping on a woman's lip are still pretty gross.Some unappreciated crude humor aside, I do recommend the film.